抗氧化剂在胎儿酒精综合征中的应用

参 考 文 献
[1] Henderson GI, Devi BG., Perez A, et al. In utero ethanol exposure elicits oxidative stress in the rat fetus. Alcohol Clin Exp Res 1995; 19(3): 714-720.
[2] Peng Y, Kwok KH, Yang PH, et al. Ascorbic acid inhibits ROS production, NF-κB activation and prevents ethanol-induced growth retardation and microencephaly. Neuropharmacology 2005; 48(3): 426-434.
[3] Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995; 41(2): 1819-1828.
[4] Heaton MB, Mitchell JJ, Paiva M. Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy. Alcohol Clin Exp Res 2000; 24(4):512-518.
[5] Marino MD, Aksenov MY, Kelly SJ. Vitamin E protects against alcohol-induced cell loss and oxidative stress in the neonatal rat hippocampus. Int J Dev Neurosci 2004; 22(5-6): 363-377.
[6] Mitchell JJ, Paiva M, Heaton MB. The antioxidants vitamin E and beta-carotene protect against ethanol-induced neurotoxicity in embryonic rat hippocampal cultures. Alcohol 1999; 17(2): 163-168.
[7] Mitchell JJ, Paiva M, Heaton MB. Vitamin E and beta-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndrome. Neurosci Lett 1999; 263(2-3): 189-192.
[8] Siler-Marsiglio KI, Pan Q, Paiva M, et al. Mitochondrially targeted vitamin E and vitamin E mitigate ethanol-mediated effects on cerebellar granule cell antioxidant defense systems. Brain Res 2005; 1052(2): 202-211.
[9] Siler-Marsiglio KI, Paiva M, Madorsky I, et al. Protective mechanisms of pycnogenol in ethanol-insulted cerebellar granule cells. J Neurobiol 2004; 61(2): 267-276.
[10] La Grange L, Wang M, Watkins R, et al. Protective effects of the flavonoid mixture, silymarin, on fetal rat brain and liver. J Ethnopharmacol 1999; 65(1): 53-61.
[11] Reid C, Edwards J, Wang M, et al. Prevention by a silymarin/phospholipid compound of ethanol-induced social learning deficits in rats. Planta Med 1999; 65(5): 421-424.
[12] Edwards J, Grange LL, Wang M, et al. Fetoprotectivity of the flavanolignan compound Siliphos against ethanol-induced toxicity. Phytother Res. 2000; 14(7): 517-521.
[13] Cano MJ, Ayala A, Murillo ML, et al. Protective effect of folic acid against oxidative stress produced in 21-day postpartum rats by maternal-ethanol chronic consumption during pregnancy and lactation period. Free Radic Res 2001; 34(1):1-8.
[14] Heaton MB, Madorsky I, Paiva M, et al. Ethanol-induced reduction of neurotrophin secretion in neonatal rat cerebellar granule cells is mitigated by vitamin E. Neurosci Lett 2004; 370(1): 51-54.
[15] Spong CY, Abebe DT, Gozes I, et al. Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. J Pharmacol Exp Ther 2001; 297(2): 774-779.