脂溢性角化病的发病机理及治疗

参 考 文 献
[1]苏金发，陈军秀，陈砚香，等.110例脂溢性角化病的临床与病理分析，中国麻风皮肤病杂志，2007,23（9）：781-782.
[2]GillD,Dorevtch A,Marks R,The prevalence of seborrheic keratoses in people aged 15 to 30 years:is the term senile keratosis redundant [J].Arch Dermatol,2000,136:759-62.
[3]Yeatman JM,Kikenny M,Marks R,The prevalence of seborrheic keratoses in an Austrakian population:dose expoure to sunlight play a part in their frequency[J].BrDermatol1997,137:411-4.
[4]郑凤兰,林元珠,梁祖琪,等.脂溢性角化病细胞核DNA含量的流式细胞分析[J].中华皮肤科杂志，1994，27（2）：96-97.
[5]Lee ES,Whang MR,Kang WH,Absence of human papillomavirus DNA in nongenital seorrheic keratosis [J].Korean Med Sci,2001,16:679-22.
[6]Boulaire J,Fotedar A,Fotedar R.The functions of the CDK2 cyclink inase inhibitor P21WAFI[J].Pathol Biol,2000,48(3):190-202.
[7]Blokx WA,de jong EM,de Wilde PC,et al.P16 and P53 expression in (pre) malignant epidermal tumors of renal transp lant recipients and immunocompent individuals [J].Mod Pathol,2003,16(9):869-78.
[8]Green CI,Khavari PA.Targets for molecular therapy of skin cancer [J].Semin Cancer Biol,2004,14(1):63-9.
[9]Nakamura S,Nishioka K.Enhanced expression of P16 in seborrheic keratosis a lesion of accumulated senescent epidermal ceiis in G1 arrest [J].BrDermatol,2003,149:560-5.
[10]Hussein MR,Al-Badaiwy ZH,Guirguis MN.Analysis of p53 and bcl-2protein expression in the nontumorgenic,pretumorigenic,and tumorigenic keratinocytic hyperoliferative lesions[J].Cutan Pathol 2004,31:643-651.
[11]Hafiner C,Hartmann A,Vogt T,FGFR3 mutations in epidermal nevi and seborrheic:lesions from urothelium and skin [J].J Invest Dermatol,2007,127(7):1572-3.
[12]Hafiner C,Lopez-Knowles E,Luis NM,et al.Oncogenic PIK3CA mutations occur epidermal nevi and seborrheic keratoses with a characteristic mutation pattem[J].Proc Natl Acad Sci USA,2007,140(33):13450-4.
[13]吴伟伟，盛晚香.细胞周期蛋白E、P16蛋白与脂溢性角化病的相关性[J].中华皮肤科杂志，2005,38:389.
[14]Bito T,Ueda M,Ito A,et al.Less expression of cyclin E in cutaneous squamous cell carcinomas than in benign and premalignant keratinocytic lesions[J].Cutan Pathol,1997,24:305-8.
[15]Tusji T,Kitajima S,Koashi Y.Expression of proliferating cell nuclear antigen(PCNA) and apoptosis related antigen(LeY) in epithelial skin tumors[J].Am Dermatopathol,1998,20:164-9.
[16]Kuwae K,Matsumoto-Miyai K,Yoshida S,Yoshidal,et al.Epidermal expression of serine protease,neuropsin(KLK8) in normal and pathological skin samples[J].Mol Pathol,2002,55:235-41.
[17]Sloan JB,Jaworsky C,Clinical misdiagnosis of squamous cell carcinoma in situ as seborrheic keratosis.A prospective study [J].Dermatol Surg Oncol,1993,19:413-6.
[18]王晓彦，萨娜，王泽民，等.磷癌与脂溢性角化病DNA倍体图像定量分析[J].中国皮肤性病学杂志，2000,14:88-9.
[19]Manaka L,Kadono S,Kawashima M,et al.The mechanism of hyperpig-mentation in seborrhoeic keratosis involves the high expression of ECE-la and TNF-a,which stimulate secretion of endothelin l[J].Br Dermatol,2001,145:895-903.
[20]Asagami C,Muto M,Hirota T,et al.Anti-tumor effects of 1,25-di-hydroxyvitam in D3[1,25(OH)2D3]in seborrheic keratosis[J].J Invest Dermatol Symp Proc,1996,1:94-6.
[21]张江安，谭升顺，袁景奕，等.他扎罗汀凝胶治疗脂溢性角化病50例[J].中华皮肤科杂志，2004，37:679.
[22]李小红，李喜英，黄蕊，等.755激光联合维A酸霜治疗脂溢性角化病72例观察.中国皮肤性病学杂志，2008,22（7）：410-411.
[23]陈龙文，陈方.化学剥脱和刮除术联合治疗脂溢性角化病[J].中国美容医学，2006,15:693-4.
[24]Burkhart CG,Burkhart CG,Use of a keratolytic agentlytic agent with occlusion for topical of hyperkeratotic seborrheic keratoses [J].Skin Med,2008,7(1):15-8.
[25]姜萍，王桂芝，姚春丽.Q开关倍频Nd:YAG激光治疗脂溢性角化病126例疗效观察.激光医学，200829（1）：18.
[26]Culbertson GR.532-nm diode laser treament of seborrheic keratoses with color enhancement [J].Dermatol Surg,2008,34(4):525-8.
[27]刘瑛琦，陈佐龙.中药治疗脂溢性角化病16例[J].中医药学报，2000,4:30-1.