β内酰胺类抗生素后效应的研究进展
PAE、PASME、SME、PLIE等理论，近年在抗生素领域开始受到重视,这些理论对全面分析抗生素的药效学特点，为进一步优化给药模式，设计更加合理有效地给药方案提供了新的理论依据，用这些理论来确定给药剂量、给药间隔时间和给药次数，使抗生素应用更加合理科学，同时可减少给药次数、提高疗效、降低不良反应以及减轻患者经济负担等方面具有很好的实用价值。如何充分利用抗生素后效应理论来指导给药方案设计, 使抗菌药在临床上得到合理应用仍需进一步研究。
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