夏枯草药理作用研究进展
1.8 活血化瘀
夏枯草能明显延长寒凝气滞急性血瘀模型大鼠的凝血酶原时间、缩短血浆优球蛋白溶解时间,对血液流变学部分指标有改善作用[27]。以夏枯草为君药具有化瘀消痰、软坚散结功效的异位胶囊[28],治疗实验性子宫内膜异位症的家兔模型,结果发现,兔异位子宫内膜腺体减少,腺腔变小,腺上皮及表面上皮呈柱状或立方形,间质稀疏;并且发现异位胶囊治疗组动物的低切全血粘度、血浆粘度、红细胞压积、血沉与对照组相比有显著性差异。王氏等[5]从夏枯草中提取夏枯草总皂甙对麻醉大鼠冠脉结扎后4 h,40 mg/kg腹腔注射,结果显示,心肌梗死范围较对照组有缩小。
2 结语
夏枯草资源丰富,药理作用广泛,有重要的临床应用价值和开发利用价值。但对于夏枯草的药理作用研究还有待深入,如夏枯草降血糖的具体机理,虽然有很多假说,但都未有明确实验数据证明。
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